Ontology highlight
ABSTRACT:
SUBMITTER: Mason MJ
PROVIDER: S-EPMC7326699 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Mason Mike J MJ Schinke Carolina C Eng Christine L P CLP Towfic Fadi F Gruber Fred F Dervan Andrew A White Brian S BS Pratapa Aditya A Guan Yuanfang Y Chen Hongjie H Cui Yi Y Li Bailiang B Yu Thomas T Chaibub Neto Elias E Mavrommatis Konstantinos K Ortiz Maria M Lyzogubov Valeriy V Bisht Kamlesh K Dai Hongyue Y HY Schmitz Frank F Flynt Erin E Dan Rozelle Danziger Samuel A SA Ratushny Alexander A Dalton William S WS Goldschmidt Hartmut H Avet-Loiseau Herve H Samur Mehmet M Hayete Boris B Sonneveld Pieter P Shain Kenneth H KH Munshi Nikhil N Auclair Daniel D Hose Dirk D Morgan Gareth G Trotter Matthew M Bassett Douglas D Goke Jonathan J Walker Brian A BA Thakurta Anjan A Guinney Justin J
Leukemia 20200214 7
While the past decade has seen meaningful improvements in clinical outcomes for multiple myeloma patients, a subset of patients does not benefit from current therapeutics for unclear reasons. Many gene expression-based models of risk have been developed, but each model uses a different combination of genes and often involves assaying many genes making them difficult to implement. We organized the Multiple Myeloma DREAM Challenge, a crowdsourced effort to develop models of rapid progression in ne ...[more]