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In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption electrospray ionization mass spectrometry imaging.


ABSTRACT: Graphical abstractThis study investigated the spatially resolved metabolic profile changes in rat kidney after the administration of aristolochic acid I (AAI) by an in situ metabolomics method based on air flow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI), providing new insights into the mechanisms underlying aristolochic acids nephrotoxicity.Image 1

SUBMITTER: Wang Z 

PROVIDER: S-EPMC7332651 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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