Ontology highlight
ABSTRACT:
SUBMITTER: Leber MF
PROVIDER: S-EPMC7333629 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Leber Mathias F MF Neault Serge S Jirovec Elise E Barkley Russell R Said Aida A Bell John C JC Ungerechts Guy G
Cytokine & growth factor reviews 20200703
Cancer immunotherapy using tumor-selective, oncolytic viruses is an emerging therapeutic option for solid and hematologic malignancies. A considerable variety of viruses ranging from small picornaviruses to large poxviruses are currently being investigated as potential candidates. In the early days of virotherapy, non-engineered wild-type or vaccine-strain viruses were employed. However, these viruses often did not fully satisfy the major criteria of safety and efficacy. Since the advent of reve ...[more]