Ontology highlight
ABSTRACT:
SUBMITTER: Schindowski C
PROVIDER: S-EPMC7337175 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Schindowski Christina C Zimmermann Jürgen J Schindowski Katharina K
Degenerative neurological and neuromuscular disease 20140905
Alzheimer's disease (AD) is a devastating neurodegenerative form of dementia with increasing incidence rates in most countries. AD is characterized by amyloid plaques and neurofibrillary tangles in the brains of AD individuals accompanied by global neuronal loss. The peptide amyloid-β (Aβ) aggregates to amyloid plaques in AD brains. As a result, many therapeutic approaches target Aβ. Human plasma and the plasma product intravenous immunoglobulin (IVIG) contain naturally-occurring anti-Aβ antibod ...[more]