RNA interference in glial cells for nerve injury treatment.
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ABSTRACT:
SUBMITTER: Lin J
PROVIDER: S-EPMC7338726 | biostudies-literature | 2020 Jan-Dec
REPOSITORIES: biostudies-literature
Publications
RNA interference in glial cells for nerve injury treatment.
Lin Junquan J Jo Seung Bin SB Kim Tae-Hyun TH Kim Hae-Won HW Chew Sing Yian SY
Journal of tissue engineering 20200101
Drivers of RNA interference are potent for manipulating gene and protein levels, which enable the restoration of dysregulated mRNA expression that is commonly associated with injuries and diseases. This review summarizes the potential of targeting neuroglial cells, using RNA interference, to treat nerve injuries sustained in the central nervous system. In addition, the various methods of delivering these RNA interference effectors will be discussed. ...[more]
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