Ontology highlight
ABSTRACT:
SUBMITTER: Kwon JH
PROVIDER: S-EPMC7345654 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Kwon Ji Hyun JH Kim Hyun Kyu HK Ha Tae Won TW Im Jeong Suk JS Song Byung Hoo BH Hong Ki Sung KS Oh Jae Sang JS Han Jaeseok J Lee Man Ryul MR
Biomedicines 20200626 6
Various types of stress stimuli have been shown to threaten the normal development of embryos during embryogenesis. Prolonged heat exposure is the most common stressor that poses a threat to embryo development. Despite the extensive investigation of heat stress control mechanisms in the cytosol, the endoplasmic reticulum (ER) heat stress response remains unclear. In this study, we used human embryonic stem cells (hESCs) to examine the effect of heat stress on early embryonic development, specifi ...[more]