Human Virus Transcriptional Regulators.
Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC7346790 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
Human Virus Transcriptional Regulators.
Liu Xing X Hong Ted T Parameswaran Sreeja S Ernst Kevin K Marazzi Ivan I Weirauch Matthew T MT Fuxman Bass Juan I JI
Cell 20200701 1
Viral genomes encode transcriptional regulators that alter the expression of viral and host genes. Despite an emerging role in human diseases, a thorough annotation of human viral transcriptional regulators (vTRs) is currently lacking, limiting our understanding of their molecular features and functions. Here, we provide a comprehensive catalog of 419 vTRs belonging to 20 different virus families. Using this catalog, we characterize shared and unique cellular genes, proteins, and pathways target ...[more]
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