Ontology highlight
ABSTRACT:
SUBMITTER: Kong Y
PROVIDER: S-EPMC7403884 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Kong Yanan Y Ou Xueqi X Li Xing X Zeng Yan Y Gao Guanfeng G Lyu Ning N Liu Peng P
Molecular therapy oncolytics 20200624
Leucine-rich-repeat-containing G protein-coupled receptor 6 (LGR6) has been identified as the stem cell marker in multiple normal tissues and malignancies. Previous studies implicated paradoxical functions of LGR6 as a tumor-suppressor gene or oncogene given to the specific context. To explore the exact role of LGR6 in triple-negative breast cancer (TNBC) that never has been studied before, in this study, we assessed LGR6 expression levels by RT-PCR and immunohistochemistry. LGR6 stable expressi ...[more]