Ontology highlight
ABSTRACT:
SUBMITTER: Giovannetti A
PROVIDER: S-EPMC7404317 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Giovannetti Antonello A Straface Elisabetta E Rosato Edoardo E Casciaro Marco M Pioggia Giovanni G Gangemi Sebastiano S
International journal of molecular sciences 20200715 14
Systemic sclerosis (SSc) is a rare chronic autoimmune disease associated with significant morbidity and mortality. Two main subsets of SSc are recognized: (i) diffuse cutaneous SSc with rapidly progressive fibrosis of the skin, lungs, and other internal organs; and (ii) limited cutaneous SSc, which is dominated by vascular manifestations, with skin and organ fibrosis generally limited and slowly progressing. In spite of intense investigation, both etiology and pathogenesis of SSc are still unkno ...[more]