Unknown

Dataset Information

0

Angiogenesis Dysregulation in the Pathogenesis of Systemic Sclerosis.

ABSTRACT: Systemic sclerosis is a chronic autoimmune connective tissue disease characterized by vascular injury and fibrosis and by an impaired angiogenesis which cannot ensure an efficient vascular recovery. Vascular injury is responsible for hypoxia and tissual ischemia which are the primary triggers for angiogenesis and are not able to induce a compensatory angiogenesis. This review article is focused on current knowledge on the mechanisms responsible for angiogenesis dysregulation in systemic sclerosis.

SUBMITTER: Cantatore FP 

PROVIDER: S-EPMC5534276 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Angiogenesis Dysregulation in the Pathogenesis of Systemic Sclerosis.

Cantatore Francesco Paolo FP   Maruotti Nicola N   Corrado Addolorata A   Ribatti Domenico D  

BioMed research international 20170716

Systemic sclerosis is a chronic autoimmune connective tissue disease characterized by vascular injury and fibrosis and by an impaired angiogenesis which cannot ensure an efficient vascular recovery. Vascular injury is responsible for hypoxia and tissual ischemia which are the primary triggers for angiogenesis and are not able to induce a compensatory angiogenesis. This review article is focused on current knowledge on the mechanisms responsible for angiogenesis dysregulation in systemic sclerosi  ...[more]

Similar Datasets

Unknown Pathogenesis of Systemic Sclerosis.
| S-EPMC4459100 | biostudies-literature
Unknown Role of Alarmins in the Pathogenesis of Systemic Sclerosis.
| S-EPMC7404317 | biostudies-literature
Unknown Systemic Sclerosis Pathogenesis and Emerging Therapies, beyond the Fibroblast.
| S-EPMC6364098 | biostudies-literature
Unknown The impact of Fli1 deficiency on the pathogenesis of systemic sclerosis.
| S-EPMC3826615 | biostudies-other
Unknown Pathogenesis of multiple sclerosis via environmental and genetic dysregulation of N-glycosylation.
| S-EPMC3960996 | biostudies-literature
Unknown Novel insights into dendritic cells in the pathogenesis of systemic sclerosis.
| S-EPMC7290079 | biostudies-literature
Unknown The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis.
| S-EPMC6753625 | biostudies-literature
Unknown Emerging Evidence Highlighting the Importance of Redox Dysregulation in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS).
| S-EPMC7929997 | biostudies-literature
Unknown Antibodies against human cytomegalovirus in the pathogenesis of systemic sclerosis: a gene array approach.
| S-EPMC1298939 | biostudies-literature
Unknown Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis.
| S-EPMC6813992 | biostudies-literature