Ontology highlight
ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC7414041 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Huang Xing X Xu Xingyuan X Wang Xun X Tang Tianyu T Li Enliang E Zhang Xiaozhen X Xu Jian J Shen Hang H Guo Chengxiang C Xu Tao T Ren Jianhong J Bai Xueli X Liang Tingbo T
Signal transduction and targeted therapy 20200807 1
Despite recent progress in hepatitis treatment, there have been no significant advances in the development of liver cancer vaccines in recent years. In this study, we investigated the regulatory effect and potential mechanism of hepatocyte growth factor receptor (MET, also known as HGFR) on tumor vaccinations for liver cancer in mice. Herein, we demonstrate that MET expression is significantly associated with the immunogenicity of liver cancer in mice and humans, and that MET depletion dramatica ...[more]