Unknown

Dataset Information

0

Initial stability of a percutaneous osseointegrated endoprosthesis with proximal interlocking screws for transhumeral amputees.


ABSTRACT:

Background

Percutaneous osseointegrated devices for skeletal fixation of prosthetic limbs have the potential to improve clinical outcomes in the transhumeral amputee population. Initial endoprosthesis stability is paramount for long-term osseointegration and safe clinical introduction of this technology. We evaluated an endoprosthetic design featuring a distally porous coated titanium stem with proximal slots for placement of bicortical interlocking screws.

Methods

Yield load, ultimate failure load, and construct stiffness were measured in 18 pairs of fresh-frozen and thawed cadaver humeri, at distal and proximal amputation levels, without and with screws, under axial pull-out, torsion, and bending loads. Paired statistical comparisons were performed without screws at the two resection levels, and at distal and proximal levels with and without screws.

Findings

Without screws, the location of the amputation influenced the stability only in torsional yield (p = 0.032) and torsional ultimate failure (p = 0.033). Proximally, the torsional yield and the torsional ultimate failure were 44% and 47% of that distally. Screws improved stability. In axial pull-out, screws increased the distal ultimate failure 3.2 times (p = 0.003). In torsion, screws increased the yield at the proximal level 1.9 times (p = 0.035), distal ultimate failure load 3.3 times (p = 0.016) and proximal ultimate failure 6.4 times (p = 0.013). In bending, screws increased ultimate failure at the proximal level 1.6 times (p = 0.026).

Interpretation

Proximal slots and bicortical interlocking screws may find application in percutaneous osseointegrated devices for patients with amputations, especially in the less stable proximal bone of a short residual limb.

SUBMITTER: Drew AJ 

PROVIDER: S-EPMC7414792 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

altmetric image

Publications

Initial stability of a percutaneous osseointegrated endoprosthesis with proximal interlocking screws for transhumeral amputees.

Drew Alex J AJ   Taylor Carolyn E CE   Tashjian Robert Z RZ   Chalmers Peter N PN   Henninger Heath B HB   Bachus Kent N KN  

Clinical biomechanics (Bristol, Avon) 20191206


<h4>Background</h4>Percutaneous osseointegrated devices for skeletal fixation of prosthetic limbs have the potential to improve clinical outcomes in the transhumeral amputee population. Initial endoprosthesis stability is paramount for long-term osseointegration and safe clinical introduction of this technology. We evaluated an endoprosthetic design featuring a distally porous coated titanium stem with proximal slots for placement of bicortical interlocking screws.<h4>Methods</h4>Yield load, ult  ...[more]

Similar Datasets

| S-EPMC8849523 | biostudies-literature
| S-EPMC7410272 | biostudies-literature
| S-EPMC10538745 | biostudies-literature
| S-EPMC7417188 | biostudies-literature
| S-EPMC11360735 | biostudies-literature
| S-EPMC5653840 | biostudies-literature
| S-EPMC6614708 | biostudies-literature
| S-EPMC9908643 | biostudies-literature
| S-EPMC7577069 | biostudies-literature
| S-EPMC5617815 | biostudies-literature