Ontology highlight
ABSTRACT:
SUBMITTER: Lobatto ME
PROVIDER: S-EPMC7460274 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Lobatto Mark E ME Binderup Tina T Robson Philip M PM Giesen Luuk F P LFP Calcagno Claudia C Witjes Julia J Fay Francois F Baxter Samantha S Wessel Chang Ho CH Eldib Mootaz M Bini Jason J Carlin Sean D SD Stroes Erik S G ESG Storm Gert G Kjaer Andreas A Lewis Jason S JS Reiner Thomas T Fayad Zahi A ZA Mulder Willem J M WJM Pérez-Medina Carlos C
Bioconjugate chemistry 20190607 2
Nanotherapy has recently emerged as an experimental treatment option for atherosclerosis. To fulfill its promise, robust noninvasive imaging approaches for subject selection and treatment evaluation are warranted. To that end, we present here a positron emission tomography (PET)-based method for quantification of liposomal nanoparticle uptake in the atherosclerotic vessel wall. We evaluated a modular procedure to label liposomal nanoparticles with the radioisotope zirconium-89 (<sup>89</sup>Zr). ...[more]