Ontology highlight
ABSTRACT:
SUBMITTER: Aroke EN
PROVIDER: S-EPMC7460556 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Aroke Edwin N EN Powell-Roach Keesha L KL Jaime-Lara Rosario B RB Tesfaye Markos M Roy Abhrarup A Jackson Pamela P Joseph Paule V PV
International journal of molecular sciences 20200818 16
Transient receptor potential (TRP) channels are a superfamily of cation transmembrane proteins that are expressed in many tissues and respond to many sensory stimuli. TRP channels play a role in sensory signaling for taste, thermosensation, mechanosensation, and nociception. Activation of TRP channels (e.g., TRPM5) in taste receptors by food/chemicals (e.g., capsaicin) is essential in the acquisition of nutrients, which fuel metabolism, growth, and development. Pain signals from these nociceptor ...[more]