Chiral Tartaric Acid Improves Fracture Toughness of Bioactive Brushite-Collagen Bone Cements.
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ABSTRACT:
SUBMITTER: Sarrigiannidis SO
PROVIDER: S-EPMC7461128 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
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Chiral Tartaric Acid Improves Fracture Toughness of Bioactive Brushite-Collagen Bone Cements.
Sarrigiannidis Stylianos O SO Moussa Hanan H Dobre Oana O Dalby Matthew J MJ Tamimi Faleh F Salmeron-Sanchez Manuel M
ACS applied bio materials 20200706 8
Brushite cements are promising bone regeneration materials with limited biological and mechanical properties. Here, we engineer a mechanically improved brushite-collagen type I cement with enhanced biological properties by use of chiral chemistry; d- and l-tartaric acid were used to limit crystal growth and increase the mechanical properties of brushite-collagen cements. The impact of the chiral molecules on the cements was examined with Fourier-transform infrared spectroscopy (FTIR), X-ray diff ...[more]
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