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Enzyme-Guided Selection and Cascaded Emergence of Nanostructured Constitutional Dynamic Networks.

ABSTRACT: Enzymes (endonucleases) are coupled to constitutional dynamic networks to stimulate the selection of a constituent and cascaded emergence of a new network. This is exemplified with the EcoRI-dictated depletion of a network and selection of a constituent that activates the cascaded emergence of a new network. The new network is further depleted by HindIII to a selected constituent that can be coupled to the cascaded emergence of a dynamic network. In addition, upon subjecting a [3 × 3] constitutional dynamic network to endonucleases EcoRI and HindIII, the programmed hierarchical selection of [2 × 2] constitutional dynamic networks followed by the biocatalytic selection of a constituent for the subsequent emergence of new networks is demonstrated.

SUBMITTER: Wang S

PROVIDER: S-EPMC7467759 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Enzyme-Guided Selection and Cascaded Emergence of Nanostructured Constitutional Dynamic Networks.

Wang Shan S Yue Liang L Willner Itamar I

Nano letters 20200615 7

Enzymes (endonucleases) are coupled to constitutional dynamic networks to stimulate the selection of a constituent and cascaded emergence of a new network. This is exemplified with the <i>Eco</i>RI-dictated depletion of a network and selection of a constituent that activates the cascaded emergence of a new network. The new network is further depleted by <i>Hin</i>dIII to a selected constituent that can be coupled to the cascaded emergence of a dynamic network. In addition, upon subjecting a [3 × ...[more]

PMID: 32515971

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