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PH-Mediated Single Molecule Conductance of Cucurbit[7]uril.

ABSTRACT: Recognition tunneling technique owns the capability for investigating and characterizing molecules at single molecule level. Here, we investigated the conductance value of cucurbit[7]uril (CB[7]) and melphalan@CB[7] (Mel@CB[7]) complex molecular junctions by using recognition tunneling technique. The conductances of CB[7] and Mel@CB[7] with different pH values were studied in aqueous media as well as organic solvent. Both pH value and guest molecule have an impact on the conductance of CB[7] molecular junction. The conductances of CB[7] and Mel@CB[7] both showed slightly difference on the conductance under different measurement systems. This work extends the molecular conductance measurement to aqueous media and provides new insights of pH-responsive host-guest system for single molecule detection through electrical measurements.

SUBMITTER: Ai Q

PROVIDER: S-EPMC7477741 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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pH-Mediated Single Molecule Conductance of Cucurbit[7]uril.

Ai Qiushuang Q Fu Qiang Q Liang Feng F

Frontiers in chemistry 20200825

Recognition tunneling technique owns the capability for investigating and characterizing molecules at single molecule level. Here, we investigated the conductance value of cucurbit[7]uril (CB[7]) and melphalan@CB[7] (Mel@CB[7]) complex molecular junctions by using recognition tunneling technique. The conductances of CB[7] and Mel@CB[7] with different pH values were studied in aqueous media as well as organic solvent. Both pH value and guest molecule have an impact on the conductance of CB[7] mol ...[more]

PMID: 33195012

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