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First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS).


ABSTRACT: We report on the first case of multiresistant Pseudomonas aeruginosa harbouring the metallo-?-lactamase IMP-15 isolated in Switzerland from a patient repatriated from Cambodia. The laboratory diagnosis of IMP-15 was hampered by two negative tests for carbapenemase detection. The carbapenemase gene was subsequently detected by whole genome sequencing and the isolate further characterised by various phenotypic and genotypic analyses.

SUBMITTER: Goldenberger D 

PROVIDER: S-EPMC7494785 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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First case of IMP-15-producing <i>Pseudomonas aeruginosa</i> in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS).

Goldenberger Daniel D   Vuichard-Gysin Danielle D   Herzog Kathrin K   Hinić Vladimira V   Seth-Smith Helena H   Egli Adrian A  

IDCases 20200902


We report on the first case of multiresistant <i>Pseudomonas aeruginosa</i> harbouring the metallo-β-lactamase IMP-15 isolated in Switzerland from a patient repatriated from Cambodia. The laboratory diagnosis of IMP-15 was hampered by two negative tests for carbapenemase detection. The carbapenemase gene was subsequently detected by whole genome sequencing and the isolate further characterised by various phenotypic and genotypic analyses. ...[more]

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