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An Acridine-Based Fluorescent Sensor for Monitoring ClO- in Water Samples and Zebrafish.

ABSTRACT: A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO- was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO- and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 ?M. Additionally, BK was satisfactorily applied for sensing ClO- in water samples and zebrafish.

SUBMITTER: Lee SC

PROVIDER: S-EPMC7506904 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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An Acridine-Based Fluorescent Sensor for Monitoring ClO- in Water Samples and Zebrafish.

Lee Su Chan SC Park Soyoung S So Haeri H Lee Gyudong G Kim Ki-Tae KT Kim Cheal C

Sensors (Basel, Switzerland) 20200823 17

A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO- was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO- and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μ ...[more]

PMID: 32842534

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