Ontology highlight
ABSTRACT:
SUBMITTER: Scharinger F
PROVIDER: S-EPMC7507862 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
ChemCatChem 20200615 14
We present a novel strategy for organocatalytic transfer hydrogenations relying on an ion-paired catalyst of natural l-amino acids as main source of chirality in combination with racemic, atropisomeric phosphoric acids as counteranion. The combination of a chiral cation with a structurally flexible anion resulted in a novel chiral framework for asymmetric transfer hydrogenations with enhanced selectivity through synergistic effects. The optimized catalytic system, in combination with a Hantzsch ...[more]