Ontology highlight
ABSTRACT:
SUBMITTER: Tao Z
PROVIDER: S-EPMC7533052 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Tao Zhennan Z Li Xuetao X Wang Hao H Chen Guangliang G Feng Zibin Z Wu Yue Y Yin Haoran H Zhao Guozheng G Deng Zhitong Z Zhao Chaohui C Li Yanyan Y Sun Ting T Zhou Youxin Y
Clinical and translational medicine 20201001 6
Bromodomain and extraterminal domain (BET) family proteins are considered to be epigenetic readers that regulate gene expression by recognizing acetyl lysine residues on histones and nonhistone chromatin factors and have been classified as curative targets for a variety of cancers. Glioma-initiating cells (GICs), which commit self-renewal, perpetual proliferation, multidirectional differentiation, and vigorous tumorigenicity, sustain the peculiar genetic and epigenetic diversification in the GBM ...[more]