Ontology highlight
ABSTRACT:
SUBMITTER: Cai H
PROVIDER: S-EPMC7551039 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Cai Huiming H Liu Ge G Zhong Jianfeng J Zheng Kai K Xiao Haitao H Li Chenyang C Song Xun X Li Ying Y Xu Chenshu C Wu Haiqiang H He Zhendan Z Zhu Qinchang Q
Viruses 20200921 9
As evidence has mounted that virus-infected cells, such as cancer cells, negatively regulate the function of T-cells via immune checkpoints, it has become increasingly clear that viral infections similarly exploit immune checkpoints as an immune system escape mechanism. Although immune checkpoint therapy has been successfully used in cancer treatment, numerous studies have suggested that such therapy may also be highly relevant for treating viral infection, especially chronic viral infections. H ...[more]