Ontology highlight
ABSTRACT:
SUBMITTER: Zhao J
PROVIDER: S-EPMC7555639 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Zhao Junwei J Santino Federica F Giacomini Daria D Gentilucci Luca L
Biomedicines 20200825 9
Integrins are a family of cell surface receptors crucial to fundamental cellular functions such as adhesion, signaling, and viability, deeply involved in a variety of diseases, including the initiation and progression of cancer, of coronary, inflammatory, or autoimmune diseases. The natural ligands of integrins are glycoproteins expressed on the cell surface or proteins of the extracellular matrix. For this reason, short peptides or peptidomimetic sequences that reproduce the integrin-binding mo ...[more]