Dataset Information

Structural Brain Architectures Match Intrinsic Functional Networks and Vary across Domains: A Study from 15 000+ Individuals.

ABSTRACT: Brain structural networks have been shown to consistently organize in functionally meaningful architectures covering the entire brain. However, to what extent brain structural architectures match the intrinsic functional networks in different functional domains remains under explored. In this study, based on independent component analysis, we revealed 45 pairs of structural-functional (S-F) component maps, distributing across nine functional domains, in both a discovery cohort (n = 6005) and a replication cohort (UK Biobank, n = 9214), providing a well-match multimodal spatial map template for public use. Further network module analysis suggested that unimodal cortical areas (e.g., somatomotor and visual networks) indicate higher S-F coherence, while heteromodal association cortices, especially the frontoparietal network (FPN), exhibit more S-F divergence. Collectively, these results suggest that the expanding and maturing brain association cortex demonstrates a higher degree of changes compared with unimodal cortex, which may lead to higher interindividual variability and lower S-F coherence.

SUBMITTER: Luo N

PROVIDER: S-EPMC7566687 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Structural Brain Architectures Match Intrinsic Functional Networks and Vary across Domains: A Study from 15 000+ Individuals.

Luo Na N Sui Jing J Abrol Anees A Chen Jiayu J Turner Jessica A JA Damaraju Eswar E Fu Zening Z Fan Lingzhong L Lin Dongdong D Zhuo Chuanjun C Xu Yong Y Glahn David C DC Rodrigue Amanda L AL Banich Marie T MT Pearlson Godfrey D GD Calhoun Vince D VD

Cerebral cortex (New York, N.Y. : 1991) 20200901 10

Brain structural networks have been shown to consistently organize in functionally meaningful architectures covering the entire brain. However, to what extent brain structural architectures match the intrinsic functional networks in different functional domains remains under explored. In this study, based on independent component analysis, we revealed 45 pairs of structural-functional (S-F) component maps, distributing across nine functional domains, in both a discovery cohort (n = 6005) and a r ...[more]

PMID: 32488253

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Dataset Information

Structural Brain Architectures Match Intrinsic Functional Networks and Vary across Domains: A Study from 15 000+ Individuals.

Publications

Structural Brain Architectures Match Intrinsic Functional Networks and Vary across Domains: A Study from 15 000+ Individuals.

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