Ontology highlight
ABSTRACT:
SUBMITTER: Lacinova L
PROVIDER: S-EPMC7567506 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Lacinova Lubica L Mallmann Robert Theodor RT Jurkovičová-Tarabová Bohumila B Klugbauer Norbert N
Channels (Austin, Tex.) 20201201 1
Voltage-gated Ca<sup>2+</sup> channels are typically integrated in a complex network of protein-protein-interactions, also referred to as Ca<sup>2+</sup> channel nanodomains. Amongst the neuronal Ca<sub>V</sub>2 channel family, Ca<sub>V</sub>2.2 is of particular importance due to its general role for signal transmission from the periphery to the central nervous system, but also due to its significance for pain perception. Thus, Ca<sub>V</sub>2.2 is an ideal target candidate to search for pharmac ...[more]