Ontology highlight
ABSTRACT:
SUBMITTER: Silva Pde M
PROVIDER: S-EPMC4620289 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Silva Priscila de Matos Pde M Bier Julia J Paiatto Lisiery Negrini LN Galdino Albuquerque Cassia C Lopes Souza Caique C Fernandes Luis Gustavo Romani LG Tamashiro Wirla Maria da Silva Cunha WM Simioni Patricia Ucelli PU
Journal of immunology research 20151012
Dendritic cells (DCs), the most important professional antigen-presenting cells (APC), play crucial role in both immunity and tolerance. It is well known that DCs are able to mount immune responses against foreign antigens and simultaneously tolerate self-antigens. Since DCs can be modulated depending on the surrounding microenvironment, they can act as a bridge between innate and adaptive immunity. However, the mechanisms that support this dual role are not entirely clear. Recent studies have s ...[more]