Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki M
PROVIDER: S-EPMC7579715 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Suzuki Motoshi M Cao Ke K Kato Seiichi S Mizutani Naoki N Tanaka Kouji K Arima Chinatsu C Tai Mei Chee MC Nakatani Norie N Yanagisawa Kiyoshi K Takeuchi Toshiyuki T Shi Hanxiao H Mizutani Yasuyoshi Y Niimi Atsuko A Taniguchi Tetsuo T Fukui Takayuki T Yokoi Kohei K Wakahara Keiko K Hasegawa Yoshinori Y Mizutani Yukiko Y Iwaki Soichiro S Fujii Satoshi S Satou Akira A Tamiya-Koizumi Keiko K Murate Takashi T Kyogashima Mamoru M Tomida Shuta S Takahashi Takashi T
Journal of cellular and molecular medicine 20200909 20
Sphingolipids constitute a class of bio-reactive molecules that transmit signals and exhibit a variety of physical properties in various cell types, though their functions in cancer pathogenesis have yet to be elucidated. Analyses of gene expression profiles of clinical specimens and a panel of cell lines revealed that the ceramide synthase gene CERS6 was overexpressed in non-small-cell lung cancer (NSCLC) tissues, while elevated expression was shown to be associated with poor prognosis and lymp ...[more]