Ontology highlight
ABSTRACT:
SUBMITTER: Scheiner S
PROVIDER: S-EPMC7582283 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20200930 19
Several cyano groups are added to an alkane, alkene, and alkyne group so as to construct a Lewis acid molecule with a positive region of electrostatic potential in the area adjoining these substituents. Although each individual cyano group produces only a weak π-hole, when two or more such groups are properly situated, they can pool their π-holes into one much more intense positive region that is located midway between them. A NH<sub>3</sub> base is attracted to this site, where it forms a stron ...[more]