Ontology highlight
ABSTRACT:
SUBMITTER: Lee JY
PROVIDER: S-EPMC7582321 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Lee Joo Young JY Lee Ji Hye JH Cheon Chong Kun CK
International journal of molecular sciences 20200929 19
Gomisin N (GN) is lignin derived from <i>Schisandra chinensis</i> that has been reported to exhibit hepato-protective, anti-cancer, and anti-inflammatory effects. However, its role in whole-body energetic homeostasis remains unclear. In this study, we employed <i>Drosophila melanogaster</i> as a diet-induced obese model to elucidate the effects of GN on lipid and glucose metabolism by measuring climbing activity, triglyceride levels, and lifespan under a rearing condition of a high-fat diet (HFD ...[more]