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Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID-19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series.


ABSTRACT:

Objective

We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions.

Methods

Basic clinical characteristics were described and the efficacy of Arbidol was evaluated based on gender, age, maximum body temperature of the patients.

Results

Basically, males had a higher risk of fever and more onset symptoms than females. Arbidol could accelerate fever recovery and viral clearance in respiratory specimens, particularly in males. Arbidol also contributed to shorter hospital stay without obvious adverse reactions.

Conclusions

In the retrospective COVID-19 cohort, gender was one of the important factors affecting patient's conditions. Arbidol showed several beneficial effects in these patients, especially in males. This study brought more researches enlightenment in understanding the emerging infectious disease.

SUBMITTER: Gao W 

PROVIDER: S-EPMC7582420 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Clinical features and efficacy of antiviral drug, Arbidol in 220 nonemergency COVID-19 patients from East-West-Lake Shelter Hospital in Wuhan: a retrospective case series.

Gao Wei W   Chen Si S   Wang Kun K   Chen Rongzhang R   Guo Qian Q   Lu Jingjing J   Wu Xiaodong X   He Yanan Y   Yan Qiaoyun Q   Wang Shengyun S   Wang Feilong F   Jin Li L   Hua Jing J   Li Qiang Q  

Virology journal 20201023 1


<h4>Objective</h4>We aimed to describe the features of 220 nonemergency (mild or common type) COVID-19 patients from a shelter hospital, as well as evaluate the efficiency of antiviral drug, Arbidol in their disease progressions.<h4>Methods</h4>Basic clinical characteristics were described and the efficacy of Arbidol was evaluated based on gender, age, maximum body temperature of the patients.<h4>Results</h4>Basically, males had a higher risk of fever and more onset symptoms than females. Arbido  ...[more]

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