Ontology highlight
ABSTRACT:
SUBMITTER: Chen YX
PROVIDER: S-EPMC7585874 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Chen Yi-Xiao YX Rong Yu Y Jiang Feng F Chen Jia-Bin JB Duan Yuan-Yuan YY Dong Shan-Shan SS Zhu Dong-Li DL Chen Hao H Yang Tie-Lin TL Dai Zhijun Z Guo Yan Y
Computational and structural biotechnology journal 20201008
Although genome-wide association studies (GWASs) have successfully identified thousands of risk variants for human complex diseases, understanding the biological function and molecular mechanisms of the associated SNPs involved in complex diseases is challenging. Here we developed a framework named integrative multi-omics network-based approach (IMNA), aiming to identify potential key genes in regulatory networks by integrating molecular interactions across multiple biological scales, including ...[more]