Ontology highlight
ABSTRACT:
SUBMITTER: Almeida RG
PROVIDER: S-EPMC7651858 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Almeida Renata G RG Valença Wagner O WO Rosa Luísa G LG de Simone Carlos A CA de Castro Solange L SL Barbosa Juliana M C JMC Pinheiro Daniel P DP Paier Carlos R K CRK de Carvalho Guilherme G C GGC Pessoa Claudia C Goulart Marilia O F MOF Kharma Ammar A da Silva Júnior Eufrânio N EN
RSC medicinal chemistry 20200713 10
<i>Ortho</i>-Quinones represent a special class of redox active compounds associated with a spectrum of pronounced biological activities, including selective cytotoxicity and antimicrobial actions. The modification of the quinone ring by simple nitrogen and sulphur substitutions leads to several new classes of compounds with their own, distinct redox behaviour and equally distinct activities against cancer cell lines and <i>Trypanosoma cruzi</i>. Some of the compounds investigated show activity ...[more]