A minimum reporting standard for multiple sequence alignments.
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ABSTRACT:
SUBMITTER: Wong TKF
PROVIDER: S-EPMC7671350 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
A minimum reporting standard for multiple sequence alignments.
Wong Thomas K F TKF Kalyaanamoorthy Subha S Meusemann Karen K Yeates David K DK Misof Bernhard B Jermiin Lars S LS
NAR genomics and bioinformatics 20200414 2
Multiple sequence alignments (MSAs) play a pivotal role in studies of molecular sequence data, but nobody has developed a minimum reporting standard (MRS) to quantify the completeness of MSAs in terms of completely specified nucleotides or amino acids. We present an MRS that relies on four simple completeness metrics. The metrics are implemented in AliStat, a program developed to support the MRS. A survey of published MSAs illustrates the benefits and unprecedented transparency offered by the MR ...[more]
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