Ontology highlight
ABSTRACT:
SUBMITTER: Sadek M
PROVIDER: S-EPMC7674043 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Sadek Mustafa M Juhas Mario M Poirel Laurent L Nordmann Patrice P
Antimicrobial agents and chemotherapy 20201117 12
Metallo-β-lactamase (MBL)-producing <i>Escherichia coli</i> isolates resistant to the newly developed β-lactam/β-lactamase inhibitor drug combination aztreonam-avibactam (ATM-AVI) have been reported. Here, we analyzed a series of 118 clinical MBL-producing <i>E. coli</i> isolates of various geographical origins for susceptibility to ATM-AVI. The nature of the PBP3 protein sequence and the occurrence of <i>bla</i><sub>CMY</sub> genes for susceptibility to ATM-AVI were investigated. We showed here ...[more]