Ontology highlight
ABSTRACT:
SUBMITTER: Plotnikov A
PROVIDER: S-EPMC7676271 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20201118 1
Differentiation therapy has been recently revisited as a prospective approach in cancer therapy by targeting the aberrant growth, and repairing the differentiation and cell death programs of cancer cells. However, differentiation therapy of solid tumors is a challenging issue and progress in this field is limited. We performed High Throughput Screening (HTS) using a novel dual multiplex assay to discover compounds, which induce differentiation of human colon cancer cells. Here we show that the p ...[more]