Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC7678816 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhang Li L Herrera Carolina C Coburn Jeannine J Olejniczak Natalia N Ziprin Paul P Kaplan David L DL LiWang Patricia J PJ
ACS biomaterials science & engineering 20170605 8
Topical microbicides have the potential to provide effective protection against sexual transmission of HIV. Challenges in developing microbicides include their application in resource-poor settings with high temperatures and a lack of refrigeration, and low user adherence to a rigorous daily regimen. Several protein-based HIV inhibitors show great promise as microbicides, being highly specific and not expected to lead to resistance that would affect the efficacy of current antiretroviral treatme ...[more]