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Porcine lymphotropic herpesvirus DNA detection in multiple organs of pigs in Brazil.

ABSTRACT: We investigated the porcine lymphotropic herpesvirus (PLHV) DNA presence in multiple organs of pigs. Biological samples (n = 136) included tissue fragments of the central nervous system, heart, kidney, liver, lungs, spleen, urinary bladder, and urine. Sixty-eight (50%) organs were PLHV DNA-positive. None of the urine samples were detected with the virus genome. Although the presence of the PLHV DNA in the urinary bladder and kidney has been detected, it was not possible to show whether urine can be considered an effective route of virus shedding. This study warns to the risk of PLHV zoonotic transmission by xenotransplantation of tissues of porcine origin.

SUBMITTER: Dall Agnol AM

PROVIDER: S-EPMC7688735 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Porcine lymphotropic herpesvirus DNA detection in multiple organs of pigs in Brazil.

Dall Agnol Alais M AM Leme Raquel A RA Suphoronski Suelen A SA Oliveira Thalita E S TES Possatti Flávia F Saporiti Viviane V Headley Selwyn A SA Alfieri Amauri Alcindo AA Alfieri Alice Fernandes AF

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 20200708 4

We investigated the porcine lymphotropic herpesvirus (PLHV) DNA presence in multiple organs of pigs. Biological samples (n = 136) included tissue fragments of the central nervous system, heart, kidney, liver, lungs, spleen, urinary bladder, and urine. Sixty-eight (50%) organs were PLHV DNA-positive. None of the urine samples were detected with the virus genome. Although the presence of the PLHV DNA in the urinary bladder and kidney has been detected, it was not possible to show whether urine can ...[more]

PMID: 32638274

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