Ontology highlight
ABSTRACT:
SUBMITTER: Rahman MA
PROVIDER: S-EPMC7691350 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Rahman Md Ajijur MA Kaiser Frank F Jamshidi Shirin S Freitas Monteiro Marta M Rahman Khondaker Miraz KM Mullany Peter P Roberts Adam P AP
Scientific reports 20201126 1
Antibiotic resistance poses an increasing threat to global health. To tackle this problem, the identification of principal reservoirs of antibiotic resistance genes (ARGs) plus an understanding of drivers for their evolutionary selection are important. During a PCR-based screen of ARGs associated with integrons in saliva-derived metagenomic DNA of healthy human volunteers, two novel variants of genes encoding a D-alanine-D-alanine ligase (ddl6 and ddl7) located within gene cassettes in the first ...[more]