Reverse Genetics System for Rabbit vesivirus.
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ABSTRACT:
SUBMITTER: Alvarez AL
PROVIDER: S-EPMC7693663 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Reverse Genetics System for <i>Rabbit vesivirus</i>.
Álvarez Ángel L ÁL García-Manso Alberto A Dalton Kevin P KP Martín-Alonso José M JM Nicieza Inés I Podadera Ana A Acosta-Zaldívar Maikel M de Llano Daniel D Parra Francisco F
Frontiers in microbiology 20201113
Most caliciviruses are refractory to replication in cell culture and only a few members of the family propagate <i>in vitro</i>. <i>Rabbit vesivirus</i> (RaV) is unique due to its ability to grow to high titers in several animal and human cell lines. This outstanding feature makes RaV an ideal candidate for reverse genetics studies, an invaluable tool to understand the molecular basis of virus replication, the biological functions of viral genes and their roles in pathogenesis. The recovery of v ...[more]
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