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External temperature sensor assisted a new low power photoplethysmography readout system for accurate measurement of the bio-signs.


ABSTRACT: This study presents an external temperature sensor assisted a new low power, time-interleave, wide dynamic range, and low DC drift photoplethysmography (PPG) signal acquisition system to obtain the accurate measurement of various bio signs in real-time. The designed chip incorporates a 2-bit control programmable transimpedance amplifier (TIA), a high order filter, a 3:8 programmable gain amplifier (PGA) and 2?×?2 organic light-emitting diode (OLED) driver. Temperature sensor is used herein to compensate the adverse effect of low-skin-temperature on the PPG signal quality. The analog front-end circuit is implemented in the integrated chip with chip area of 2008 ?m?×?1377 ?m and fabricated via TSMC T18 process. With the standard 1.8 V, the experimental result shows that the measured current sensing range is 20 nA-100 uA. The measured dynamic range of the designed readout circuit is 80 dB. The estimated signal to noise ratio is 60 dB@1 uA, and the measured input referred noise is 60.2 pA/Hz½. The total power consumption of the designed chip is 31.32 µW (readout)?+?1.62 mW (OLED driver@100% duty cycle). The non-invasive PPG sensor is applied to the wrist artery of the 40 healthy subjects for sensing the pulsation of the blood vessel. The experimental results show that for every 1 °C decrease in mean ambient temperature tends to 0.06 beats/min, 0.125 mmHg and 0.063 mmHg increase in hear rate (HR), systolic (SBP) and diastolic (DBP), respectively. Similarly, for every 1 °C increase in mean ambient temperature tends to 0.13 beats/min, 0.601 mmHg?and 0.121 mmHg increase in HR, SBP and DBP, respectively. The measured accuracy and standard error for the HR estimation are 96%, and -?0.022?±?2.589 beats/minute, respectively. The oxygen stauration (SpO2) measurement results shows that the mean absolute percentage error is less than 5%. The resultant errors for the SBP and DBP measurement are -?0.318?±?5.19 mmHg and -?0.5?±?1.91 mmHg, respectively.

SUBMITTER: Pandey RK 

PROVIDER: S-EPMC7695241 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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External temperature sensor assisted a new low power photoplethysmography readout system for accurate measurement of the bio-signs.

Pandey Rajeev Kumar RK   Chao Paul C-P PC  

Microsystem technologies : sensors, actuators, systems integration 20201127 6


This study presents an external temperature sensor assisted a new low power, time-interleave, wide dynamic range, and low DC drift photoplethysmography (PPG) signal acquisition system to obtain the accurate measurement of various bio signs in real-time. The designed chip incorporates a 2-bit control programmable transimpedance amplifier (TIA), a high order filter, a 3:8 programmable gain amplifier (PGA) and 2 × 2 organic light-emitting diode (OLED) driver. Temperature sensor is used herein to co  ...[more]

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