Ontology highlight
ABSTRACT:
SUBMITTER: Ma J
PROVIDER: S-EPMC7696096 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20201115 22
Photocages have been successfully applied in cellular signaling studies for the controlled release of metabolites with high spatio-temporal resolution. Commonly, coumarin photocages are activated by UV light and the quantum yields of uncaging are relatively low, which can limit their applications in vivo. Here, syntheses, the determination of the photophysical properties, and quantum chemical calculations of 7-diethylamino-4-hydroxymethyl-thiocoumarin (thio-DEACM) and caged adenine nucleotides a ...[more]