Ontology highlight
ABSTRACT:
SUBMITTER: Lin WY
PROVIDER: S-EPMC7697548 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Lin Wen-Ying WY Wang Hsin-Hui HH Chen Yi-Wei YW Lin Chun-Fu CF Fan Hueng-Chuen HC Lee Yi-Yen YY
International journal of molecular sciences 20201117 22
With advances in the understanding of characteristics of molecules, specific antigens on the surface of hematological malignant cells were identified and multiple therapies targeting these antigens as neoplasm treatments were developed. Among them, chimeric antigen receptor (CAR) T-cell therapy, which got United States Food and Drug Administration (FDA) approval for relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL) as well as for recurrent acute lymphoblastic leukemia (ALL) within ...[more]