Ontology highlight
ABSTRACT:
SUBMITTER: Kisu I
PROVIDER: S-EPMC7698480 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Kisu Iori I Kato Yojiro Y Masugi Yohei Y Ishigaki Hirohito H Yamada Yohei Y Matsubara Kentaro K Obara Hideaki H Emoto Katsura K Matoba Yusuke Y Adachi Masataka M Banno Kouji K Saiki Yoko Y Sasamura Takako T Itagaki Iori I Kawamoto Ikuo I Iwatani Chizuru C Nakagawa Takahiro T Murase Mitsuru M Tsuchiya Hideaki H Urano Hiroyuki H Ema Masatsugu M Ogasawara Kazumasa K Aoki Daisuke D Nakagawa Kenshi K Shiina Takashi T
Journal of clinical medicine 20201117 11
Delivery following uterus transplantation (UTx)-an approach for treating uterine factor infertility-has not been reported in nonhuman primate models. Here, six female major histocompatibility complex (MHC)-defined cynomolgus macaques that underwent allogeneic UTx were evaluated. Antithymocyte globulin and rituximab were administered to induce immunosuppression and a triple maintenance regimen was used. Menstruation resumed in all animals with long-term survival, except one, which was euthanized ...[more]