Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC7714077 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Zhang Xi X Zeng Jianming J Tong Yin Y Zhang Li L Lu Xibin X Zhu Shenglang S Li Zhoufang Z
FEBS open bio 20201120 12
Immunoglobulin (Ig) A nephropathy (IgAN) is the most common glomerulonephritis, which is characterized by the deposition of IgA antibody in the glomerulus. Systematic dissection of immune composition may contribute to a better understanding of the alternations in the immune system in IgAN. To this end, here we applied immune repertoire sequencing technology for parallel analysis of the complementary determining region 3 (CDR3) of all B cell receptors, including all five antibody subtypes (IgA, I ...[more]