The Versatility of Sirtuin-1 in Endocrinology and Immunology.
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ABSTRACT:
SUBMITTER: Rasha F
PROVIDER: S-EPMC7717970 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
The Versatility of Sirtuin-1 in Endocrinology and Immunology.
Rasha Fahmida F Mims Brianyell McDaniel BM Castro-Piedras Isabel I Barnes Betsy J BJ Grisham Matthew B MB Rahman Rakhshanda Layeequr RL Pruitt Kevin K
Frontiers in cell and developmental biology 20201119
Sirtuins belong to the class III family of NAD-dependent histone deacetylases (HDAC) and are involved in diverse physiological processes that range from regulation of metabolism and endocrine function to coordination of immunity and cellular responses to stress. Sirtuin-1 (SIRT1) is the most well-studied family member and has been shown to be critically involved in epigenetics, immunology, and endocrinology. The versatile roles of SIRT1 include regulation of energy sensing metabolic homeostasis, ...[more]
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