Ontology highlight
ABSTRACT:
SUBMITTER: Yildiz S
PROVIDER: S-EPMC7723408 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Yildiz Soner S Pereira Bonifacio Lopes João P JP Bergé Matthieu M González-Ruiz Víctor V Baud Damian D Kloehn Joachim J Boal-Carvalho Inês I Schaeren Olivier P OP Schotsaert Michael M Hathaway Lucy J LJ Rudaz Serge S Viollier Patrick H PH Hapfelmeier Siegfried S Francois Patrice P Schmolke Mirco M
eLife 20201208
Under eubiotic conditions commensal microbes are known to provide a competitive barrier against invading bacterial pathogens in the intestinal tract, on the skin or on the vaginal mucosa. Here, we evaluate the role of lung microbiota in Pneumococcus colonization of the lungs. In eubiosis, the lungs of mice were dominantly colonized by <i>Lactobacillus murinus</i>. Differential analysis of 16S rRNA gene sequencing or <i>L. murinus-</i>specific qPCR of DNA from total organ homogenates <i>vs.</i>br ...[more]