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Retrospective Analysis of the Relationship between Two Anthrax Outbreaks in Kazakhstan Based on Genomic Data.


ABSTRACT: We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (MLVA), canonical single-nucleotide polymorphism (CanSNP) analysis, and genome-wide analysis demonstrated that the outbreaks were not connected.

SUBMITTER: Shevtsov A 

PROVIDER: S-EPMC7729412 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Retrospective Analysis of the Relationship between Two Anthrax Outbreaks in Kazakhstan Based on Genomic Data.

Shevtsov Alexandr A   Vergnaud Gilles G   Amirgazin Asylulan A   Lukhnova Larissa L   Izbanova Uinkul U   Shevtsov Vladislav V   Ramankulov Yerlan Y  

Microbiology resource announcements 20201210 50


We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (MLVA), canonical single-nucleotide polymorphism (CanSNP) analysis, and genome-wide analysis demonstrated that the outbreaks were not connected. ...[more]

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