The Multifaceted Nature of Streptococcal Antigen I/II Proteins in Colonization and Disease Pathogenesis.
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ABSTRACT:
SUBMITTER: Manzer HS
PROVIDER: S-EPMC7732690 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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The Multifaceted Nature of Streptococcal Antigen I/II Proteins in Colonization and Disease Pathogenesis.
Manzer Haider S HS Nobbs Angela H AH Doran Kelly S KS
Frontiers in microbiology 20201125
Streptococci are Gram-positive bacteria that belong to the natural microbiota of humans and animals. Certain streptococcal species are known as opportunistic pathogens with the potential to cause severe invasive disease. Antigen I/II (AgI/II) family proteins are sortase anchored cell surface adhesins that are nearly ubiquitous across streptococci and contribute to many streptococcal diseases, including dental caries, respiratory tract infections, and meningitis. They appear to be multifunctional ...[more]
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