Ontology highlight
ABSTRACT:
SUBMITTER: Chevalier G
PROVIDER: S-EPMC7732982 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Chevalier Grégoire G Siopi Eleni E Guenin-Macé Laure L Pascal Maud M Laval Thomas T Rifflet Aline A Boneca Ivo Gomperts IG Demangel Caroline C Colsch Benoit B Pruvost Alain A Chu-Van Emeline E Messager Aurélie A Leulier François F Lepousez Gabriel G Eberl Gérard G Lledo Pierre-Marie PM
Nature communications 20201211 1
Depression is the leading cause of disability worldwide. Recent observations have revealed an association between mood disorders and alterations of the intestinal microbiota. Here, using unpredictable chronic mild stress (UCMS) as a mouse model of depression, we show that UCMS mice display phenotypic alterations, which could be transferred from UCMS donors to naïve recipient mice by fecal microbiota transplantation. The cellular and behavioral alterations observed in recipient mice were accompan ...[more]