Ontology highlight
ABSTRACT:
SUBMITTER: Mao M
PROVIDER: S-EPMC7747957 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Mao Mao M Chang Chun-Chi CC Pickar-Oliver Adrian A Cervia Lisa D LD Wang Liangli L Ji Jing J Liton Paloma B PB Gersbach Charles A CA Yuan Fan F
Advanced biosystems 20200721 8
Cell engineering relies heavily on viral vectors for the delivery of molecular cargo into cells due to their superior efficiency compared to nonviral ones. However, viruses are immunogenic and expensive to manufacture, and have limited delivery capacity. Nonviral delivery approaches avoid these limitations but are currently inefficient for clinical applications. This work demonstrates that the efficiency of nonviral delivery of plasmid DNA, mRNA, Sleeping Beauty transposon, and ribonucleoprotein ...[more]